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Studies in man indicate that the peak concentration in the aqueous humour is reached about two hours after topical administrationAfter topical application in monkeyslatanoprost is distributed primarily in the anterior segmentthe conjunctivae and the eyelidsOnly minute quantities of the drug reach the posterior segment.
If you are wearing contact lensesremove them before using this medicationWait at least 15 minutes before replacing your contact lenses.
Latanoprost is a prostanoid selective FP receptor agonist that is believed to reduce the intraocular pressureIOPby increasing the outflow of aqueous humorStudies in animals and man suggest that the main mechanism of action is increased uveoscleral outflowElevated IOP represents a major risk factor for glaucomatous field lossThe higher the level of IOPthe greater the likelihood of optic nerve damage and visual field loss.
A very serious allergic reaction to this drug is rareHoweverget medical help right away if you notice any symptoms of a serious allergic reactionincludingrashsevere itching/swellingespecially of the face/tongue/throatdizzinesstrouble breathing.
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